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2-Azidoadenosine CAS NO 59587-07-4
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CAS No.:59587-07-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Azidoadenosine is a chemically modified nucleoside analog, a crucial building block in synthetic organic chemistry and biochemical research. Its value lies in the reactive azido group, which enables efficient click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), for labeling and conjugation. This compound is essential for researchers and manufacturers in pharmaceutical development, proteomics, and nucleic acid chemistry, where it is used to create probes, modify biomolecules, and develop novel therapeutic agents.
Application
- Bioconjugation and Probe Synthesis: Acts as a key reagent for site-specifically labeling oligonucleotides, proteins, and other biomolecules via click chemistry.
- Pharmaceutical Research: Serves as a versatile intermediate in the synthesis of nucleoside-based drug candidates and prodrugs.
- Chemical Biology Studies: Used to incorporate photoaffinity or reporter tags into nucleotides for studying nucleic acid-protein interactions and metabolic pathways.
- Materials Science: Facilitates the surface functionalization of nanomaterials and polymers with bioactive nucleosides.
- Diagnostic Development: Employed in creating labeled nucleotides for diagnostic assays and sequencing technologies.
Basic Information
| Product Name | 2-Azidoadenosine |
| CAS No. | 59587-07-4 |
| Molecular Formula | C10H12N8O4 |
| Molecular Weight | 308.26 g/mol |
| Synonyms | 2-Azido-9-β-D-ribofuranosyl-9H-adenine; 2-Azido-9-β-D-ribofuranosyladenine; 2-Azido-adenosine; 2-N3-Adenosine; 2-Azidoadenosine riboside; Adenosine, 2-azido- |
| EINECS | Contact for details |
Quality Control
Our 2-Azidoadenosine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥95% |
| Water Content (KF) | ≤5.0% |
| Solubility | Soluble in DMSO, DMF; Slightly soluble in water |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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