Description

Griseusin B is a bioactive secondary metabolite belonging to the pyranonaphthoquinone class of compounds. This compound is valued for its significant biological activity, particularly as a potent antibiotic and antitumor agent, making it a crucial intermediate in pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel antimicrobial and anticancer therapeutics.

Application

• Pharmaceutical Research: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of new antibiotic and antitumor drugs.
• Antimicrobial Agent Development: Investigated for its efficacy against Gram-positive bacteria and other resistant microbial strains.
• Oncology Research: Studied for its mechanism of action and potential in cancer cell line inhibition and apoptosis induction.
• Biochemical Studies: Used as a tool compound to study cellular processes, enzyme inhibition, and signal transduction pathways.
• Academic & Institutional Research: Employed in universities and research labs for fundamental studies in natural product chemistry and medicinal chemistry.

Basic Information

Product Name	Griseusin B
CAS No.	59554-12-0
Molecular Formula	C30H32O10
Molecular Weight	552.57 g/mol
Synonyms	Griseusin B; Antibiotic Griseusin B; 5,8-Dihydroxy-2-(1-hydroxyethyl)naphtho[2,3-c]pyran-4,9-dione; 3,4-Dihydro-3,8,10-trihydroxy-3-methyl-1H-naphtho[2,3-c]pyran-7,12-dione; 1,2,3,4-Tetrahydro-1,8,10-trihydroxy-1-methylbenzo[g]isochromene-5,10-dione; NSC 339586; LIA 0735 B
EINECS	Contact for details

Quality Control

Our Griseusin B is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available upon request, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.