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2-Azido-2-Deoxy-3-O,4-o-Dibenzyl-6-o-Acetyl-α-D-Galactopyranosyl Bromide CAS NO 59464-24-3
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CAS No.:59464-24-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Azido-2-Deoxy-3-O,4-o-Dibenzyl-6-o-Acetyl-α-D-Galactopyranosyl Bromide is a sophisticated glycosyl bromide donor, a critical building block in synthetic carbohydrate chemistry. Its value lies in its protected and activated structure, enabling precise, high-yielding glycosylation reactions for constructing complex oligosaccharides and glycoconjugates. This intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutics, vaccines, and diagnostic tools.
Application
- Glycosylation Reagent: A key donor molecule for the stereoselective synthesis of α-linked galactosamine derivatives and complex oligosaccharides.
- Pharmaceutical Intermediate: Used in the research and development of glycoprotein-based drugs, anticancer agents, and carbohydrate-based vaccines.
- Glycoconjugate Synthesis: Facilitates the creation of neoglycoconjugates for studying carbohydrate-protein interactions and cell signaling.
- Chemical Biology Probes: Serves as a precursor for "click chemistry" applications via its azido group, enabling bioconjugation and labeling.
- Oligosaccharide Library Construction: Enables automated and combinatorial synthesis for drug discovery screening against various biological targets.
Basic Information
| Product Name | 2-Azido-2-Deoxy-3-O,4-o-Dibenzyl-6-o-Acetyl-α-D-Galactopyranosyl Bromide |
| CAS No. | 59464-24-3 |
| Molecular Formula | C22H24BrN3O5 |
| Molecular Weight | 490.35 g/mol |
| Synonyms | 2-Azido-2-deoxy-3,4-di-O-benzyl-6-O-acetyl-α-D-galactopyranosyl bromide; 3,4-Di-O-benzyl-6-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyl bromide; 2-Azido-3,4-di-O-benzyl-6-O-acetyl-2-deoxy-α-D-galactopyranosyl bromide; Galactosyl bromide donor; α-D-Galactopyranosyl bromide, 2-azido-2-deoxy-3,4-di-O-benzyl-6-O-acetyl-; Glycosyl bromide donor CAS 59464-24-3 |
| EINECS | Contact for details |
Quality Control
Every batch of 2-Azido-2-Deoxy-3-O,4-o-Dibenzyl-6-o-Acetyl-α-D-Galactopyranosyl Bromide is synthesized and purified under controlled conditions to ensure high chemical purity and consistent performance. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent decomposition and oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from heat and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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