Description

5-S'-[(R)-2-Amino-2-Carboxyethyl]-5'-Thioinosine is a specialized nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. This compound matters as a key intermediate or reference standard in the synthesis and study of modified nucleotides, which are crucial for exploring novel therapeutic pathways. It is primarily needed by research institutions and pharmaceutical companies focused on antiviral drug discovery, metabolic pathway analysis, and the development of nucleotide-based prodrugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, particularly those involving purine metabolism and salvage pathways.
• Prodrug Development: Investigated for its potential in designing targeted prodrugs that improve the bioavailability and efficacy of nucleoside-based therapies.
• Metabolite Analysis: Employed in analytical laboratories for the identification and quantification of related metabolites in biological samples via HPLC or LC-MS methods.
• Enzyme Inhibition Studies: Acts as a potential inhibitor or modulator for specific enzymes involved in nucleotide synthesis, aiding in mechanistic studies.

Basic Information

Product Name	5-S'-[(R)-2-Amino-2-Carboxyethyl]-5'-Thioinosine
CAS No.	59453-11-1
Molecular Formula	C₁₂H₁₅N₅O₆S
Molecular Weight	357.34 g/mol
Synonyms	5'-S-[(R)-2-Amino-2-carboxyethyl]-5'-thioinosine; 5'-Deoxy-5'-[(R)-2-amino-2-carboxyethylthio]inosine; NSC 329853; 5'-Thioinosine, 5'-[(R)-2-amino-2-carboxyethyl]-; (R)-5'-S-(2-Amino-2-carboxyethyl)-5'-thioinosine; 5'-S-Carboxycysteaminyl-5'-deoxyinosine
EINECS	Contact for details

Quality Control

Our 5-S'-[(R)-2-Amino-2-Carboxyethyl]-5'-Thioinosine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place, ideally at controlled room temperature (15-25°C). For long-term storage, consider desiccants or inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.