Description

1H-Imidazole-4,5-Dicarbonyldichloride(9Ci) is a highly reactive, bifunctional acid chloride derivative of imidazole, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient construction of complex heterocyclic systems and functionalized imidazole scaffolds, which are pivotal in modern pharmaceutical and materials chemistry. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinases and other enzymes.
• Agrochemical Synthesis: Building block for creating new fungicides, herbicides, and plant growth regulators with imidazole-based activity.
• Ligand and Catalyst Development: Used to prepare sophisticated N-heterocyclic carbene (NHC) precursors and other specialized ligands for catalysis.
• Polymer and Material Science: Monomer for synthesizing polyimides, polyamides, and other high-performance polymers with thermal and chemical stability.
• Chemical Biology Probes: Facilitates the creation of tagged molecules and activity-based probes for studying biological processes.
• Coordination Chemistry: Serves as a linker for constructing metal-organic frameworks (MOFs) and other coordination polymers.

Basic Information

Product Name	1H-Imidazole-4,5-Dicarbonyldichloride(9Ci)
CAS No.	59399-36-9
Molecular Formula	C5H2Cl2N2O2
Molecular Weight	192.99 g/mol
Synonyms	4,5-Imidazoledicarboxylic Acid Dichloride; Imidazole-4,5-dicarbonyl Dichloride; 1H-Imidazole-4,5-dicarboxylic Acid Dichloride; 4,5-Dicarboxyimidazole Dichloride; 59399-36-9; 4,5-Imidazoledicarbonyl Chloride
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4,5-Dicarbonyldichloride(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.