Description

5-Chloro-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Imidazole-4-Car Boxamide is a sophisticated nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleoside metabolism. It is essential for medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors who require high-purity, structurally complex intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Antiviral Agent Research: Used in the development of compounds targeting viral polymerases and reverse transcriptases.
• Oncology Drug Discovery: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to nucleoside and nucleotide metabolism.
• Prodrug Development: Utilized in the design of prodrugs to enhance the bioavailability and targeting of active nucleoside analogs.
• Chemical Biology Probes: Acts as a starting material for creating labeled or modified probes to study biological pathways.

Basic Information

Product Name	5-Chloro-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Imidazole-4-Car Boxamide
CAS No.	59353-97-8
Molecular Formula	C9H12ClN3O6
Molecular Weight	293.66 g/mol
Synonyms	5-Chloro-1-(2,3-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-imidazole-4-carboxamide; 5-Chloro-1-(β-D-ribofuranosyl)imidazole-4-carboxamide; 5-Chloro-1-ribofuranosylimidazole-4-carboxamide; 5-Cl-RICA; 5-Chloro-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; 5-Chloro-1-(β-D-ribofuranosyl)imidazole-4-carboxylic acid amide; 5-Chloro-1-ribosylimidazole-4-carboxamide
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Imidazole-4-Car Boxamide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.