Description

5-Hydroxy-1-(β-D-Ribofuranosyl)-1,2,3-Triazole-4-Carboxamide is a specialized nucleoside analog with a fused triazole-carboxamide structure, representing a high-value building block in advanced chemical synthesis. This compound is critical for researchers and manufacturers developing novel pharmaceutical agents and biochemical probes, particularly in antiviral and anticancer research. It is primarily sought after by fine chemical suppliers, contract research organizations (CROs), and pharmaceutical R&D departments engaged in nucleoside chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel nucleoside-based therapeutics, including potential antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and nucleic acid biochemistry.
• Medicinal Chemistry: Acts as a versatile scaffold for structure-activity relationship (SAR) studies and the development of targeted molecular libraries.
• Academic Research: Employed in universities and research institutes for studying modified nucleosides, their mechanisms of action, and their incorporation into oligonucleotides.
• Diagnostic Probe Development: Utilized in the design and synthesis of labeled probes for molecular diagnostics and imaging applications.
• Fine Chemical Synthesis: A valuable building block for custom synthesis services catering to the life sciences industry.

Basic Information

Item	Details
Product Name	5-Hydroxy-1-(β-D-Ribofuranosyl)-1,2,3-Triazole-4-Carboxamide
CAS No.	59343-64-5
Molecular Formula	C8H12N4O6
Molecular Weight	260.21 g/mol
Synonyms	1-(β-D-Ribofuranosyl)-5-hydroxy-1H-1,2,3-triazole-4-carboxamide; 5-Hydroxy-1-(β-D-ribofuranosyl)-1H-1,2,3-triazole-4-carboxamide; 1-(β-D-Ribofuranosyl)-5-hydroxy-1,2,3-triazole-4-carboxamide; Ribofuranosyl triazole carboxamide; 5-Hydroxy-1-ribofuranosyl-1,2,3-triazole-4-carboxamide; 59343-64-5; 1H-1,2,3-Triazole-4-carboxamide, 5-hydroxy-1-β-D-ribofuranosyl-
EINECS	Contact for details

Quality Control

Our production of 5-Hydroxy-1-(β-D-Ribofuranosyl)-1,2,3-Triazole-4-Carboxamide adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal quality standards. Specifications can be aligned with common pharmacopeial guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.