Description

2-Pyridinecarbonyl Chloride, 5-Nitro- (9Ci) is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in the strategic introduction of both a reactive acid chloride group and a nitro substituent onto the pyridine ring, enabling precise molecular construction. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting the central nervous system or possessing antimicrobial activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the pyridine core is a common structural motif.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the development of functional polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and other tools for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Pyridinecarbonyl Chloride, 5-Nitro- (9Ci)
CAS No.	59290-88-9
Molecular Formula	C6H3ClN2O3
Molecular Weight	186.55 g/mol
Synonyms	5-Nitropicolinoyl Chloride; 5-Nitro-2-pyridinecarbonyl chloride; 5-Nitropyridine-2-carbonyl chloride; 2-Pyridinecarbonyl chloride, 5-nitro-; 5-Nitro-2-pyridylcarbonyl chloride; 5-Nitropicolinic acid chloride; 5-Nitropyridine-2-carboxylic acid chloride; 2-Carbamoyl-5-nitropyridine (related)
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridinecarbonyl Chloride, 5-Nitro- (9Ci) is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and documentation, making this material suitable for regulated research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.