Description

4-Pyridinecarbonyl Chloride, 3-Nitro- (9Ci) is a specialized nitro-substituted pyridine derivative that serves as a high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for targeted synthesis and scale-up projects.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific activity profiles.
• Ligand and Catalyst Preparation: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of functional polymers and organic electronic materials due to its electron-withdrawing nitro and acid chloride functionalities.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and activity-based probes for studying enzyme function and biological mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	4-Pyridinecarbonyl Chloride, 3-Nitro- (9Ci)
CAS No.	59290-83-4
Molecular Formula	C6H3ClN2O3
Molecular Weight	186.55 g/mol
Synonyms	3-Nitroisonicotinoyl chloride; 3-Nitro-4-pyridinecarbonyl chloride; 3-Nitroisonicotinic acid chloride; 4-Pyridinecarbonyl chloride, 3-nitro-; Isonicotinoyl chloride, 3-nitro-; 3-Nitro-4-pyridoyl chloride; 3-Nitroisonicotinic chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinecarbonyl Chloride, 3-Nitro- is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.