Description

1-β-D-Arabinofuranosyl-4-Heptadecanoylaminopyrimidin-2(1H)-One is a specialized nucleoside analog with a long-chain fatty acyl modification. This compound is valued for its role as a key intermediate in the synthesis of novel antiviral and anticancer agents, where its unique structure allows for targeted biological activity. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and advanced academic research institutions focused on developing next-generation therapeutic nucleosides.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of experimental antiviral and antineoplastic (anticancer) nucleoside analogs.
• Biochemical Research: Used in studies investigating enzyme-substrate interactions, particularly with nucleoside kinases and polymerases.
• Prodrug Development: Serves as a precursor for lipid-conjugated prodrugs designed to enhance cellular uptake and bioavailability.
• Antiviral Agent Synthesis: A key starting material in the research and development pipeline for novel compounds targeting DNA viruses.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside-based therapeutics.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1-β-D-Arabinofuranosyl-4-Heptadecanoylaminopyrimidin-2(1H)-One
CAS No.	59252-37-8
Molecular Formula	C26H43N3O6
Molecular Weight	493.64 g/mol
Synonyms	4-Heptadecanoylamino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone; 1-(β-D-Arabinofuranosyl)-4-heptadecanoylaminopyrimidin-2(1H)-one; N-Heptadecanoylcytosine β-D-arabinofuranoside; Ara-C17; Lipid-modified cytarabine analog; Long-chain acyl cytarabine; N4-Heptadecanoyl-1-β-D-arabinofuranosylcytosine
EINECS	Contact for details

Quality Control

Our 1-β-D-Arabinofuranosyl-4-Heptadecanoylaminopyrimidin-2(1H)-One is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality guidelines to support our global clientele in pharmaceutical and biotechnology sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.