Description

Laurocapram is a high-purity, synthetic azacycloalkane widely recognized as a highly effective skin penetration enhancer. Its primary value lies in its ability to significantly increase the transdermal absorption of active pharmaceutical ingredients, making it a critical component in advanced topical and transdermal drug delivery systems. This compound is essential for formulators and manufacturers in the pharmaceutical, cosmetic, and veterinary industries seeking to improve the bioavailability and efficacy of their products.

Application

• Transdermal Drug Delivery Systems: A key excipient in patches and gels to enhance the skin permeation of APIs like hormones, analgesics, and anti-inflammatory drugs.
• Topical Pharmaceuticals: Used in creams, ointments, and lotions to improve the delivery of antifungal, antiviral, and corticosteroid agents.
• Cosmetic & Skincare Formulations: Enhances the penetration of anti-aging compounds, vitamins, and moisturizers in serums and creams.
• Veterinary Medicine: Incorporated into topical preparations for animals to boost the absorption of therapeutic agents.
• Research & Development: Serves as a standard penetration enhancer in preclinical studies for evaluating new transdermal candidates.
• Hair Care Products: Can be used to improve the delivery of active ingredients into the scalp and hair follicles.

Basic Information

Product Name	Laurocapram
CAS No.	59227-89-3
Molecular Formula	C18H35NO
Molecular Weight	281.48 g/mol
Synonyms	1-Dodecylazacycloheptan-2-one; Azone; N-Dodecylcaprolactam; Dodecyl hexahydro-2H-azepin-2-one; 1-Dodecyl-2-pyrrolidinone (common misnomer); Kollisolv GDL; Penetration Enhancer Azone; Laurocapram [USAN]
EINECS	261-668-9

Quality Control

Our Laurocapram is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including identification, assay, and impurity profiling, to ensure it meets high-purity standards suitable for pharmaceutical and cosmetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0 %
Refractive Index (n20D)	1.470 - 1.475
Specific Gravity (20°C)	0.910 - 0.920
Water Content (KF)	≤ 0.5 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.