Description

2-(7-Methyl-1H-Indol-3-Yl)-2-Oxoacetyl Chloride is a specialized high-purity chemical building block, essential for advanced organic synthesis. This compound is valued for its reactive acid chloride group, which enables efficient coupling reactions to construct complex molecular architectures. It is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting indole-based scaffolds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the indole moiety is a critical structural component.
• Organic Synthesis Reagent: Serves as a versatile acylating agent in academic and industrial laboratories for creating amides, esters, and other carbonyl derivatives.
• Bioconjugation Chemistry: Potential use in modifying biomolecules or polymers due to its reactive functional group, applicable in materials science and biotech research.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	2-(7-Methyl-1H-Indol-3-Yl)-2-Oxoacetyl Chloride
CAS No.	59022-69-4
Molecular Formula	C12H8ClNO2
Molecular Weight	233.65 g/mol
Synonyms	2-(7-Methyl-1H-indol-3-yl)-2-oxoacetyl chloride; 2-(7-Methylindol-3-yl)-2-oxoacetyl chloride; 7-Methyl-3-indoleglyoxyloyl chloride; 7-Methylindole-3-glyoxylic acid chloride; α-Oxo-7-methyl-1H-indole-3-acetyl chloride; 59022-69-4; 2-Oxo-2-(7-methyl-1H-indol-3-yl)acetyl chloride
EINECS	Contact for details

Quality Control

Our 2-(7-Methyl-1H-Indol-3-Yl)-2-Oxoacetyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.