Description

(E)-5-(2-Carbomethoxyvinyl)Uridine is a modified nucleoside analog of significant interest in medicinal chemistry and biochemical research. This compound serves as a crucial synthetic intermediate and building block for the development of novel antiviral and anticancer agents. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on nucleoside chemistry and drug discovery. Its unique structure allows for the exploration of novel therapeutic pathways targeting viral polymerases and cellular enzymes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases and polymerases.
• Pro-drug Development: Serves as a precursor molecule for designing more bioavailable or targeted pro-drug formulations.
• Antiviral Agent Synthesis: Integral in the research and development pipeline for compounds targeting viruses such as herpesviruses and hepatitis.
• Labeled Compound Synthesis: Used as a starting material for preparing isotopically labeled (e.g., C13, N15) nucleosides for metabolic tracing studies.
• Molecular Biology Tool: Potential use in creating modified oligonucleotides for probing nucleic acid structure and function.

Basic Information

Product Name	(E)-5-(2-Carbomethoxyvinyl)Uridine
CAS No.	58931-19-4
Molecular Formula	C13H16N2O8
Molecular Weight	328.27 g/mol
Synonyms	5-(2-Carbomethoxyethenyl)uridine; 5-[(1E)-2-(Methoxycarbonyl)ethenyl]uridine; (E)-5-[2-(Methoxycarbonyl)vinyl]uridine; 5-(2-Carbomethoxyvinyl)uridine (E-isomer); Uridine, 5-[(E)-2-(methoxycarbonyl)ethenyl]-; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-[(E)-3-methoxy-3-oxoprop-1-enyl]pyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our (E)-5-(2-Carbomethoxyvinyl)Uridine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, IR) for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.