Description

Chlorocarbonic Acid-(1-Ethyl-Butyl Ester) is a specialized organic chloroformate ester, a key reagent in synthetic organic chemistry. This compound is valued for its role as a versatile acylating and chloroformylating agent, enabling the efficient introduction of the 1-ethylbutyloxycarbonyl protecting group. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the 1-ethylbutyloxycarbonyl (EboC) protecting group in multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the manufacture of advanced pesticide and herbicide intermediates, leveraging its reactivity for constructing specific carbamate or carbonate linkages.
• Peptide Chemistry: Serves as a reagent for the temporary protection of amino groups during solid-phase or solution-phase peptide synthesis.
• Polymer Modification: Employed as a functionalization agent to introduce carbonate or urethane groups into polymer backbones for specialty materials.
• Organic Synthesis Reagent: A versatile acylating agent in laboratory-scale and pilot-scale reactions for preparing esters, carbonates, and carbamates.
• Chemical Research & Development: Essential for process development and route scouting in medicinal chemistry and material science research.

Basic Information

Product Name	Chlorocarbonic Acid-(1-Ethyl-Butyl Ester)
CAS No.	58906-64-2
Molecular Formula	C7H13ClO2
Molecular Weight	164.63 g/mol
Synonyms	1-Ethylbutyl Chloroformate; 1-Ethylbutyl Carbonochloridate; Chloroformic Acid 1-Ethylbutyl Ester; 3-Pentyl Chloroformate; Pentan-3-yl Chloroformate; EboC-Cl; NSC 163045
EINECS	Contact for details

Quality Control

Our Chlorocarbonic Acid-(1-Ethyl-Butyl Ester) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize stability. This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) and away from heat, ignition sources, and incompatible materials such as bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Acidity (Titration)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.