Description

Benzeneethanethioyl Chloride, α-Oxo- (9Ci) CAS NO 58861-73-7 is a specialized organosulfur reagent featuring a highly reactive thioyl chloride group adjacent to a carbonyl function. This compound is a critical building block in organic synthesis, valued for its ability to introduce the thioester moiety and facilitate subsequent transformations. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key reagent for the synthesis of thioesters, amides, and heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in constructing sulfur-containing active ingredients for herbicides, fungicides, and insecticides.
• Peptide Mimetics & Conjugation: Facilitates the creation of thioester-linked peptide analogs and bioconjugates for drug discovery.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific sulfur-based properties.
• Chemical Biology Probes: Serves as a precursor for activity-based probes and other tools used to study enzyme function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise sulfur incorporation.

Basic Information

Product Name	Benzeneethanethioyl Chloride, α-Oxo- (9Ci)
CAS No.	58861-73-7
Molecular Formula	C8H5ClOS
Molecular Weight	184.64 g/mol
Synonyms	2-Oxo-2-phenyl-ethanethioyl chloride; Phenylglyoxalyl thiochloride; α-Oxobenzeneethanethioyl chloride; Benzoylformyl thiochloride; Phenylglyoxylic acid thiochloride; (Oxophenylacetyl) thiochloride; Thiobenzoylformyl chloride
EINECS	Contact for details

Quality Control

Our production of Benzeneethanethioyl Chloride, α-Oxo- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Yellow to light brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.