Description

Ambruticin CAS NO 58857-02-6 is a specialized antifungal compound belonging to the class of polyketide antibiotics. This product is valued for its potent activity against systemic fungal pathogens, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by biotechnology firms, pharmaceutical manufacturers, and academic research institutions focused on developing novel antifungal therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of investigational antifungal drugs targeting deep-seated mycoses.
• Biomedical Research: Used as a reference standard and active agent in in vitro and in vivo studies to understand fungal pathogenesis and evaluate therapeutic efficacy.
• Antifungal Agent Development: A crucial starting material for medicinal chemistry programs aimed at creating new derivatives with improved pharmacokinetic profiles.
• Microbiology & Diagnostics: Employed in laboratory settings for susceptibility testing and as a tool compound to study fungal resistance mechanisms.

Basic Information

Product Name	Ambruticin
CAS No.	58857-02-6
Molecular Formula	C23H34O5
Molecular Weight	390.51 g/mol
Synonyms	Ambruticin; Ambruticin S; Antibiotic WIN 64867; WIN 64867; 2-Butenoic acid, 2-methyl-, 6-[(1E,3E,5E,7E)-8-[(2S,3R,4R,5S,6R)-3,4-dihydroxy-6-methyl-5-[(1E)-1-propen-1-yl]oxan-2-yl]-8-oxoocta-1,3,5,7-tetraen-1-yl]-5-hydroxy-4,4,7a-trimethyl-2,4,5,6,7,7a-hexahydro-1-benzofuran-3-yl ester; (2S,3R,4R,5S,6R)-2-[(2E,4E,6E,8E)-9-[(3S,5R,7aS)-3-[(2E)-2-Methylbut-2-enoyloxy]-5-hydroxy-4,4,7a-trimethyl-2,4,5,6,7,7a-hexahydro-1-benzofuran-6-yl]-9-oxonona-2,4,6,8-tetraen-1-yl]-6-methyl-5-[(1E)-prop-1-en-1-yl]oxane-3,4-diol
EINECS	Contact for details

Quality Control

Our Ambruticin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.