Description

(25S)-1β,3β,21,23α,24β-Pentahydroxy-15-Oxo-18-Norspirosta-5(6),13(14)-Diene is a high-purity, structurally complex steroidal sapogenin derivative, valued for its role as a critical synthetic intermediate in advanced pharmaceutical research. Its unique pentahydroxy-oxo-norspirostadiene structure makes it a versatile building block for the development of novel therapeutic agents. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of steroid-based drugs, including potential anti-inflammatory, anti-cancer, and hormonal therapies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new drug candidates targeting various receptors.
• Reference Standard: Employed as an analytical standard in HPLC and LC-MS methods for quality control and metabolic studies of related steroid compounds.
• Biochemical Research: Utilized in enzymatic studies and as a probe to investigate steroid biosynthesis pathways and biological activity.
• Process Development: Acts as a model compound for developing and optimizing scalable synthetic routes for complex steroidal molecules.

Basic Information

Product Name	(25S)-1β,3β,21,23α,24β-Pentahydroxy-15-Oxo-18-Norspirosta-5(6),13(14)-Diene
CAS No.	58809-10-2
Molecular Formula	C26H36O7
Molecular Weight	460.56 g/mol
Synonyms	18-Nor-(25S)-1β,3β,21,23α,24β-pentahydroxy-15-oxospirosta-5,13-diene; 15-Oxo-1β,3β,21,23α,24β-pentahydroxy-18-norspirosta-5,13-diene; (25S)-18-Norspirosta-5,13-diene-1β,3β,21,23α,24β-pentol-15-one; Pentahydroxy-15-oxo-18-norspirostadiene; 58809-10-2; Steroidal sapogenin derivative; 15-Keto-norspirostadiene pentol
EINECS	Contact for details

Quality Control

Every batch of (25S)-1β,3β,21,23α,24β-Pentahydroxy-15-Oxo-18-Norspirosta-5(6),13(14)-Diene is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for research and development purposes. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results from HPLC, NMR, and MS analysis. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to maintain long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.