Description

4-Bromo-2-Thiophenecarbonyl Chloride is a versatile and highly reactive organosulfur building block, primarily used as a key intermediate in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 4-bromo-2-thiophene moiety into target molecules, enabling the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, including herbicides and fungicides with specific activity profiles.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand & Catalyst Development: Employed in the preparation of specialized thiophene-based ligands for transition metal catalysis and coordination chemistry.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new heterocyclic chemistry and synthesizing complex molecular architectures.

Basic Information

Product Name	4-Bromo-2-Thiophenecarbonyl Chloride
CAS No.	58777-65-4
Molecular Formula	C5H2BrClOS
Molecular Weight	225.49 g/mol
Synonyms	4-Bromo-2-thiophenecarboxylic acid chloride; 4-Bromothiophene-2-carbonyl chloride; 2-Thenoyl chloride, 4-bromo-; 4-Bromo-2-thenoyl chloride; 4-Bromothiophene-2-carboxylic acid chloride; 4-Bromo-2-carboxythiophene chloride; 4-Bromothiophene-2-carbonyl chloride; (4-Bromothiophen-2-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Thiophenecarbonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide detailed Certificates of Analysis (COA) with every shipment, guaranteeing traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.