Description

2,4,6-Triiodo-3-(Methylacetamido)-5-[(Methylamino)Carbonyl]Benzoyl Chloride is a high-purity, iodinated organic intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its role as a versatile building block for creating complex molecules with specific biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and life sciences industries for developing novel diagnostic agents and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of iodinated X-ray contrast media and other diagnostic imaging agents.
• API Synthesis: Used in the research and development of novel active pharmaceutical ingredients, particularly those requiring a dense, iodine-containing aromatic core.
• Chemical Research: Serves as a specialized reagent in organic chemistry for introducing the triiodobenzoyl moiety into target molecules.
• Life Sciences: Employed in the development of molecular probes and tracers for biochemical and medical research applications.
• Radiopharmaceuticals: Potential use as a starting material or intermediate in the development of compounds for nuclear medicine.

Basic Information

Product Name	2,4,6-Triiodo-3-(Methylacetamido)-5-[(Methylamino)Carbonyl]Benzoyl Chloride
CAS No.	58763-17-0
Molecular Formula	C12H9ClI3N2O3
Molecular Weight	662.38 g/mol
Synonyms	5-(Methylcarbamoyl)-2,4,6-triiodo-3-(N-methylacetamido)benzoyl chloride; 3-Acetamido-2,4,6-triiodo-5-(N-methylcarbamoyl)benzoyl chloride; Iopamidol Impurity; Iopamidol Related Compound; Iopamidol Intermediate; Benzoyl chloride, 3-(acetylmethylamino)-5-[(methylamino)carbonyl]-2,4,6-triiodo-; Iopamidol Acid Chloride
EINECS	Contact for details

Quality Control

Our 2,4,6-Triiodo-3-(Methylacetamido)-5-[(Methylamino)Carbonyl]Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.