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(2R,3S,4R,5R)-2-(Aminomethyl)-5-(6-(Benzylamino)-1H-Purin-9(6H)-Yl)Tetrahydrofuran-3,4-Diol CAS NO 58611-58-8
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CAS No.:58611-58-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(2R,3S,4R,5R)-2-(Aminomethyl)-5-(6-(Benzylamino)-1H-Purin-9(6H)-Yl)Tetrahydrofuran-3,4-Diol is a high-purity nucleoside analog derivative, a critical building block in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and functional groups, which make it an essential intermediate in the synthesis of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of antiviral drugs, anticancer therapies, and other nucleotide-based medicines.
Application
- Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel antiviral and anticancer nucleotide analogs.
- Antiviral Drug Development: Used in the research of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
- Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis.
- Precision Medicine: Employed in the development of targeted therapies that require specific stereochemical configurations for efficacy.
- Academic Research: Utilized in university and institutional labs for studying nucleoside chemistry and mechanism of action.
- Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of synthetic routes for complex APIs.
Basic Information
| Item | Details |
|---|---|
| Product Name | (2R,3S,4R,5R)-2-(Aminomethyl)-5-(6-(Benzylamino)-1H-Purin-9(6H)-Yl)Tetrahydrofuran-3,4-Diol |
| CAS No. | 58611-58-8 |
| Molecular Formula | C18H22N6O4 |
| Molecular Weight | 386.41 g/mol |
| Synonyms | 6-(Benzylamino)-9-[(2R,3S,4R,5R)-5-[(aminomethyl)tetrahydrofuran-2,3,4-triol-2-yl]purine; 6-Benzylaminopurine Riboside Derivative; N6-Benzyladenosine Analog; 9-((2R,3S,4R,5R)-5-(Aminomethyl)-3,4-dihydroxytetrahydrofuran-2-yl)-6-(benzylamino)-9H-purine; 6-Benzylamino-9-(5'-deoxy-5'-aminomethyl-β-D-ribofuranosyl)purine; Bn6-Ado Derivative; Contact for additional synonyms. |
| EINECS | Contact for details |
Quality Control
Our (2R,3S,4R,5R)-2-(Aminomethyl)-5-(6-(Benzylamino)-1H-Purin-9(6H)-Yl)Tetrahydrofuran-3,4-Diol is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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