Description

7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, (1R,2R,4R)-Rel- (9Ci) is a high-value, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid bicyclic structure and reactive acid chloride functionality make it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients, nucleoside analogs, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Nucleoside & Nucleotide Chemistry: Serves as a versatile precursor for modified nucleosides and related bioactive compounds.
• Ligand & Catalyst Development: Employed in the construction of chiral ligands for asymmetric catalysis and organometallic complexes.
• Polymer Science: Can be incorporated as a monomer or cross-linking agent for specialty polymers with unique thermal or mechanical properties.
• Academic & Process R&D: A valuable tool for methodological studies in organic chemistry and scale-up process development.

Basic Information

Item	Detail
Product Name	7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, (1R,2R,4R)-Rel- (9Ci)
CAS No.	58564-80-0
Molecular Formula	C7H7ClO2
Molecular Weight	158.58 g/mol
Synonyms	(1R,2R,4R)-7-Oxabicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; rel-(1R,2R,4R)-7-Oxabicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; 7-Oxabicyclo[2.2.1]hept-5-ene-2-carbonyl chloride, (1R,2R,4R)-rel-; 7-Oxabicyclo[2.2.1]hept-5-ene-2-carbonyl chloride, (1R,2R,4R)-; 7-Oxanorborn-5-ene-2-carbonyl chloride, (1R,2R,4R)-rel-; (1R,2R,4R)-rel-7-Oxabicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; 58564-80-0; (1R,2R,4R)-7-Oxanorborn-5-ene-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, (1R,2R,4R)-Rel- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to meet the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2R,4R)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.