Description

Tricyclo[3.2.1.02,4]Oct-6-Ene-3-Carbonyl Chloride, (1Alpha,2Alpha,3Alpha,4Alpha,5Alpha)- (9Ci) is a highly functionalized, strained bicyclic organic building block characterized by its reactive acid chloride group and unique stereochemistry. This compound matters as a key chiral synthon for constructing complex molecular architectures in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for the synthesis of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where its rigid, strained structure contributes to unique biological activity.
• Material Science Research: Acts as a monomer or cross-linking agent for developing specialty polymers with tailored thermal and mechanical properties.
• Asymmetric Catalysis Ligand Precursor: Utilized to construct complex, chiral ligands for transition metal catalysis.
• Academic & R&D Laboratories: Employed in methodological studies and the exploration of new chemical spaces due to its challenging and reactive functional groups.
• Fine Chemical Production: Incorporated into the multi-step synthesis of complex fragrance and flavor molecules.

Basic Information

Product Name	Tricyclo[3.2.1.02,4]Oct-6-Ene-3-Carbonyl Chloride, (1Alpha,2Alpha,3Alpha,4Alpha,5Alpha)- (9Ci)
CAS No.	58560-46-6
Molecular Formula	C9H9ClO
Molecular Weight	168.62 g/mol
Synonyms	(1α,2α,3α,4α,5α)-Tricyclo[3.2.1.02,4]oct-6-ene-3-carbonyl chloride; (1R,2R,3R,4R,5R)-Bicyclo[2.2.2]oct-5-ene-2-carbonyl chloride (incorrect but common misnomer); 3-Carbonylchloridotricyclo[3.2.1.02,4]oct-6-en; Tricyclo[3.2.1.02,4]oct-6-ene-3-carbonyl chloride, (1α,2α,3α,4α,5α)-; 58560-46-6; Bicyclo[2.2.2]oct-5-ene-2-carbonyl chloride, (1R,2R,3R,4R,5R)- (related isomer).
EINECS	Contact for details

Quality Control

Our production of Tricyclo[3.2.1.02,4]Oct-6-Ene-3-Carbonyl Chloride adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We operate under a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.