Description

Uridine, 2',5'-Dideoxy-5'-Iodo- is a modified nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a critical building block and a versatile intermediate in the synthesis of more complex nucleoside derivatives and potential therapeutic agents. It is primarily utilized by research scientists and development chemists in the fields of medicinal chemistry, antiviral research, and molecular biology. The product is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Medicinal Chemistry Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleoside metabolism and related pathways.
• Antiviral Agent Development: Serves as a structural scaffold for creating analogs that target viral polymerases, particularly for RNA viruses.
• Molecular Probe Synthesis: Facilitates the creation of labeled or tagged nucleosides for diagnostic and imaging applications.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex, biologically active molecules.

Basic Information

Product Name	Uridine, 2',5'-Dideoxy-5'-Iodo-
CAS No.	58510-66-0
Molecular Formula	C9H11IN2O5
Molecular Weight	354.10 g/mol
Synonyms	5'-Iodo-2',5'-dideoxyuridine; 2',5'-Dideoxy-5'-iodouridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(iodomethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione; 5'-Deoxy-5'-iodouridine; 5'-Iodo-5'-deoxyuridine; 2'-Deoxy-5'-iodouridine (common misnomer); IDU (in context of related analogs); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Uridine, 2',5'-Dideoxy-5'-Iodo- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.