Description

Amphotericin B-Deoxycholate is a polyene antifungal antibiotic complex, widely recognized as the gold standard for treating severe systemic fungal infections. Its primary value lies in its broad-spectrum fungicidal activity, particularly against life-threatening pathogens like *Aspergillus* and *Candida* species. This compound is essential for pharmaceutical manufacturers, research institutions, and contract development organizations involved in producing injectable antifungal formulations, developing novel drug delivery systems, and conducting microbiological research.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of lyophilized powder for injection, used to treat invasive fungal infections.
• Hospital & Clinical Formulations: Serves as the critical raw material for compounding intravenous antifungal therapies in hospital pharmacies.
• Biomedical Research: Used as a standard antifungal agent in microbiological assays, antifungal susceptibility testing, and studies on fungal cell membrane ergosterol.
• Drug Delivery Development: Investigated in research for developing liposomal, lipid complex, and other novel formulations to reduce toxicity and improve efficacy.
• Reference Standard: Employed as a high-purity chemical standard in quality control laboratories for HPLC and other analytical methods.
• Veterinary Medicine: Applied in the development of antifungal treatments for serious fungal infections in animals.

Basic Information

Product Name	Amphotericin B-Deoxycholate
CAS No.	58501-21-6
Molecular Formula	C47H73NO17 • C24H40O4
Molecular Weight	924.08 g/mol (Amphotericin B) + 392.57 g/mol (Deoxycholate)
Synonyms	Amphotericin B Desoxycholate; Amphotericin B Deoxycholic Acid Complex; Fungizone; Amphocin; Amphotericin B Sodium Deoxycholate Complex; Amphotericin B-DOC; ABDC; Antifungal Antibiotic from *Streptomyces nodosus*
EINECS	Contact for details

Quality Control

Our Amphotericin B-Deoxycholate is manufactured and tested to meet stringent standards suitable for pharmaceutical research and development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system ensures traceability and consistency. Certificates of Analysis are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 750 µg/mg (on dried basis)
Loss on Drying	≤ 5.0 %
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 5.0 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.