Description

(22R)-2β,3β,14,19,20,22,25-Heptahydroxy-5β-Cholest-7-En-6-One is a highly functionalized steroidal compound of significant interest in advanced pharmaceutical and biochemical research. Its complex polyhydroxylated structure makes it a valuable intermediate for the synthesis of bioactive molecules and a reference standard for analytical studies. This compound is primarily sought by research institutions and pharmaceutical developers working on steroid-based therapeutics, metabolic pathway analysis, and high-purity chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-derived drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in metabolic studies, enzyme inhibition assays, and receptor binding research.
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new synthetic routes and studying structure-activity relationships (SAR).

Basic Information

Product Name	(22R)-2β,3β,14,19,20,22,25-Heptahydroxy-5β-Cholest-7-En-6-One
CAS No.	58347-83-4
Molecular Formula	C₂₇H₄₄O₈
Molecular Weight	508.64 g/mol
Synonyms	2β,3β,14,19,20,22,25-Heptahydroxycholest-7-en-6-one; (22R)-Heptahydroxycholestenone; 5β-Cholest-7-ene-2β,3β,14,19,20,22,25-heptol-6-one; Polyhydroxylated Cholestene Derivative; Steroid Heptol Derivative; CAS 58347-83-4
EINECS	Contact for details

Quality Control

Our production of (22R)-2β,3β,14,19,20,22,25-Heptahydroxy-5β-Cholest-7-En-6-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support research and development with materials that meet the exacting standards required for pharmaceutical intermediates and analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.