Description

Cyclobutanecarbonyl Chloride, 1-Butyl- (9Ci) is a specialized organic acid chloride derivative of cyclobutane. This compound serves as a critical high-purity building block in advanced organic synthesis, enabling the introduction of the cyclobutylcarbonyl moiety. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the cyclobutane ring contributes to specific biological activity.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with unique thermal and mechanical properties.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of organic electronic materials and advanced display components.
• Peptide & Protein Modification: Employed as an acylating agent for modifying amino acids, peptides, or proteins in biochemical research.
• Catalyst & Ligand Development: Used to create novel organometallic catalysts and ligands for asymmetric synthesis.
• Flavor & Fragrance Industry: Intermediate for synthesizing complex aroma chemicals and musk analogs.
• Academic & Contract Research: Essential for methodological development and exploratory chemistry in research institutions and CROs.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 1-Butyl- (9Ci)
CAS No.	58148-17-7
Molecular Formula	C9H15ClO
Molecular Weight	174.67 g/mol
Synonyms	1-Butylcyclobutanecarbonyl Chloride; Butylcyclobutanecarbonyl Chloride; 1-Butylcyclobutane-1-carbonyl Chloride; 1-Butyl-1-cyclobutanecarbonyl Chloride; Cyclobutanecarboxylic Acid, 1-Butyl-, Chloride; 1-Butylcyclobutylcarbonyl Chloride; 1-Butylcyclobutanoyl Chloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Chloride, 1-Butyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to maintain purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.05 g/cm³
Refractive Index (n20D)	~1.460

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.