Description

(8α,13α)-3-Methoxy-1,3,5(10)-Estratrien-17-One is a high-purity steroid derivative, specifically a methoxy-substituted estratriene, identified by CAS NO 58072-53-0. This compound serves as a critical advanced pharmaceutical intermediate for the research and synthesis of complex steroid-based active pharmaceutical ingredients (APIs). It is essential for pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing hormone therapies, oncology treatments, and other specialized medicinal compounds.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of steroidal drugs and hormone analogs.
• Research & Development: Used in academic and industrial laboratories for investigating novel steroid receptor modulators and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals for advanced material science and biotechnology applications.

Basic Information

Product Name	(8α,13α)-3-Methoxy-1,3,5(10)-Estratrien-17-One
CAS No.	58072-53-0
Molecular Formula	C19H24O2
Molecular Weight	284.39 g/mol
Synonyms	3-Methoxyestra-1,3,5(10)-trien-17-one; 3-Methoxy-1,3,5(10)-estratrien-17-one; 3-Methoxyestra-1,3,5(10),16-tetraen-17-ol (related); 17-Oxo-3-methoxyestra-1,3,5(10)-triene; 3-Methoxyestra-1,3,5(10)-triene-17-one; Estra-1,3,5(10)-triene-17-one, 3-methoxy-; 3-Methoxy-19-norpregna-1,3,5(10)-trien-20-one
EINECS	Contact for details

Quality Control

Our (8α,13α)-3-Methoxy-1,3,5(10)-Estratrien-17-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be kept in secondary packaging or a dark storage cabinet to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.