Description

Benzoyl Chloride, 4-Fluoro-2-Hydroxy- (9Ci) is a specialized aromatic acid chloride derivative, distinguished by the presence of both fluorine and hydroxyl substituents on the benzene ring. This unique molecular structure makes it a highly valuable and versatile building block for synthesizing complex organic molecules, particularly in the development of advanced pharmaceuticals and agrochemicals. It is primarily sought after by research chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated benzoyl moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can improve pesticidal activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification Agent: Employed to introduce fluorinated aromatic groups into polymer chains, altering properties like chemical resistance, thermal stability, and surface energy.
• Dye & Pigment Intermediate: Facilitates the synthesis of specialized fluorinated dyes and pigments with unique color fastness and optical properties.
• Research & Development: A critical reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.

Basic Information

Product Name	Benzoyl Chloride, 4-Fluoro-2-Hydroxy- (9Ci)
CAS No.	57976-99-5
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	4-Fluoro-2-hydroxybenzoyl chloride; 2-Hydroxy-4-fluorobenzoyl chloride; 4-Fluoro-2-hydroxybenzoic acid chloride; 2-Hydroxy-4-fluorobenzoic acid chloride; 4-Fluoro-2-hydroxybenzenecarbonyl chloride; 4-Fluoro-2-hydroxybenzoyl chloride (9CI); 4-Fluoro-2-hydroxybenzoyl chloride, 9CI; 4-Fluoro-2-hydroxy-benzoyl chloride
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride, 4-Fluoro-2-Hydroxy- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay (by HPLC), identity (by IR and NMR), and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.