Description

(3S,8S,9S,10R,13R,14R,17R)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-2,3,4,7,8,9,11,12,14,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol is a high-purity, defined stereoisomer of a sterol derivative, serving as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. Its precise stereochemistry is essential for ensuring the efficacy and safety of target molecules in drug development pipelines. This compound is primarily required by manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for producing active pharmaceutical ingredients (APIs), reference standards, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of steroid-based drugs and hormone therapies.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research and development (R&D) laboratories for method development and validation.
• Biochemical Research: Employed in studies of sterol metabolism, receptor binding assays, and as a precursor in metabolic pathway investigations.
• Fine Chemical Synthesis: Serves as a starting material or intermediate for creating complex, value-added specialty chemicals with specific stereochemical requirements.
• Active Pharmaceutical Ingredient (API) Development: Integral to the research and scale-up processes for new steroid-derived therapeutic compounds.

Basic Information

Product Name	(3S,8S,9S,10R,13R,14R,17R)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-2,3,4,7,8,9,11,12,14,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol
CAS No.	57759-45-2
Molecular Formula	C27H46O
Molecular Weight	386.66 g/mol
Synonyms	Cholestan-3-ol, (3β,5α)-; (3β,5α)-Cholestan-3-ol; 5α-Cholestan-3β-ol; Dihydrocholesterol; 3β-Hydroxy-5α-cholestane; NSC 8798; Coprostanol (5α-isomer); 5α-Cholestanol
EINECS	Contact for details

Quality Control

Our (3S,8S,9S,10R,13R,14R,17R)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-2,3,4,7,8,9,11,12,14,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.