Description

Deoxyguanosine-5'-Tri-3'-Diphosphate is a specialized nucleotide analog of significant importance in biochemical research and pharmaceutical development. Its unique structure, featuring a triphosphate group at the 5' position and a diphosphate at the 3' position, makes it a valuable tool for studying enzyme mechanisms, nucleic acid metabolism, and as a potential precursor in the synthesis of novel therapeutic agents. This high-purity compound is essential for researchers and manufacturers in the fields of molecular biology, enzymology, and nucleotide-based drug discovery who require reliable, well-characterized biochemical building blocks.

Application

• Enzymology Research: Used as a substrate or inhibitor to study the kinetics and mechanisms of kinases, polymerases, and other nucleotide-processing enzymes.
• Nucleic Acid Metabolism Studies: Serves as a critical probe for investigating pathways of DNA repair, replication, and nucleotide salvage.
• Pharmaceutical Intermediate: Acts as a potential precursor in the synthesis of novel antiviral or anticancer nucleotide analogs.
• Biochemical Assay Development: Employed in the development of high-throughput screening assays for drug discovery targeting nucleotide-binding proteins.
• Diagnostic Reagent Manufacturing: Can be utilized in the production of specialized reagents for molecular diagnostics and research kits.
• Academic & Institutional Research: Provides a key material for fundamental research in biochemistry and cell biology laboratories worldwide.

Basic Information

Product Name	Deoxyguanosine-5'-Tri-3'-Diphosphate
CAS No.	57716-91-3
Molecular Formula	C10H17N5O13P5
Molecular Weight	605.15 g/mol
Synonyms	dGTP-3'-DP; 2'-Deoxyguanosine-5'-triphosphate 3'-diphosphate; Guanosine 5'-(tetrahydrogen triphosphate) 3'-(dihydrogen diphosphate), 2'-deoxy-; P1-(2'-Deoxyguanosin-5'-yl) P3,P4-bis(phosphono) trihydrogen triphosphate; Deoxy-GTP-3'-diphosphate; dGTP(3')pp
EINECS	Contact for details

Quality Control

Our Deoxyguanosine-5'-Tri-3'-Diphosphate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or moisture will lead to degradation. For long-term stability, store desiccated under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	Contact for details
Endotoxin (LAL)	< 10 EU/mg (if required)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.