Description

2,1-Benzisothiazole-3-Carbonyl Chloride (9Ci) is a high-purity, reactive chemical intermediate characterized by its acid chloride functionality. This compound is a critical building block in advanced organic synthesis, enabling the efficient introduction of the benzisothiazole pharmacophore. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the benzisothiazole scaffold for biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex heterocyclic dyes and functional colorants.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in proteomics and diagnostic research.

Basic Information

Product Name	2,1-Benzisothiazole-3-Carbonyl Chloride (9Ci)
CAS No.	57676-11-6
Molecular Formula	C8H4ClNOS
Molecular Weight	197.64 g/mol
Synonyms	2,1-Benzisothiazole-3-carbonyl chloride; 1,2-Benzisothiazole-3-carbonyl chloride; 3-Chlorocarbonyl-1,2-benzisothiazole; Benzisothiazole-3-carbonyl chloride; 2,1-Benzisothiazol-3-yl carbonyl chloride; 1,2-Benzisothiazol-3-carbonyl chloride; 3-(Chlorocarbonyl)-1,2-benzisothiazole
EINECS	Contact for details

Quality Control

Our 2,1-Benzisothiazole-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.