Description

6-Hydroxy Nicotinoyl Chloride is a versatile and reactive nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its acyl chloride functionality, which enables efficient coupling reactions for the introduction of the 6-hydroxynicotinoyl moiety. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting metabolic and neurological pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides and insecticides with improved efficacy.
• Bioconjugation Reagent: Facilitates the labeling and modification of biomolecules (e.g., peptides, proteins) for research and diagnostic applications.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functional polymers and advanced organic materials with specific electronic properties.
• Chemical Research: A valuable reagent for academic and industrial R&D in heterocyclic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	6-Hydroxy Nicotinoyl Chloride
CAS No.	57659-03-7
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	6-Hydroxynicotinoyl chloride; 6-Hydroxypyridine-3-carbonyl chloride; 3-Pyridinecarbonyl chloride, 6-hydroxy-; 6-Hydroxynicotinic acid chloride; 6-Hydroxy-3-pyridinecarbonyl chloride; Nicotinoyl chloride, 6-hydroxy-
EINECS	Contact for details

Quality Control

Our 6-Hydroxy Nicotinoyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. We employ advanced analytical techniques including HPLC, NMR, and IR spectroscopy for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.