Description

(13R,22R)-13,14:18,20-Diepoxy-14,18,22-Trihydroxy-1-Oxo-13,14-Secoergosta-2,5,24-Trien-26-Oic Acid 26,22-Lactone is a complex, highly functionalized ergostane-type steroidal lactone. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its intricate polycyclic framework and multiple reactive oxygen functionalities. It serves as a critical intermediate or reference standard for researchers and manufacturers in the life sciences sector, particularly those developing novel therapeutic agents or studying sterol biosynthesis pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroidal drugs and bioactive molecules.
• Biochemical Research: Used as a reference standard or probe in studies of enzyme inhibition, particularly those related to sterol metabolism and biosynthesis.
• Organic Synthesis: Acts as a sophisticated starting material for the preparation of complex natural product analogs and derivatives for structure-activity relationship (SAR) studies.
• Academic Research: Employed in university and institutional laboratories for methodological development in total synthesis and chemical biology projects.
• Reference Material: Provides a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	(13R,22R)-13,14:18,20-Diepoxy-14,18,22-Trihydroxy-1-Oxo-13,14-Secoergosta-2,5,24-Trien-26-Oic Acid 26,22-Lactone
CAS No.	57485-60-6
Molecular Formula	C₂₈H₃₆O₈
Molecular Weight	500.59 g/mol
Synonyms	13,14-Secoergosta-2,5,24-trien-26-oic acid, 13,14:18,20-diepoxy-14,18,22-trihydroxy-1-oxo-, 26,22-lactone, (13R,22R)-; 13,14:18,20-Diepoxy-14,18,22-trihydroxy-1-oxo-13,14-secoergosta-2,5,24-trien-26-oic acid 26,22-lactone; Steroidal seco-lactone derivative; Ergostane triepoxide lactone.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications, and specifications can be tailored to meet specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.