Description

(22R)-14,20,22-Trihydroxy-1-Oxoergosta-2,5,24-Triene-18,26-Dioic Acid 18,20:26,22-Dilactone is a complex steroidal lactone derivative with significant biological activity. This compound is valued for its role as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought by research institutions and pharmaceutical companies focused on metabolic studies, steroid chemistry, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug discovery and manufacturing.
• Biochemical Research: Serves as a crucial intermediate or probe in studying steroid biosynthesis pathways and enzyme inhibition.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a sophisticated building block for the synthesis of complex steroidal drug candidates.
• Academic Research: Utilized in university and institutional labs for chemical and pharmacological studies related to natural product derivatives.
• Metabolite Studies: Employed as an analytical standard for the identification and quantification of steroidal metabolites in biological samples.

Basic Information

Product Name	(22R)-14,20,22-Trihydroxy-1-Oxoergosta-2,5,24-Triene-18,26-Dioic Acid 18,20:26,22-Dilactone
CAS No.	57423-72-0
Molecular Formula	C28H34O8
Molecular Weight	498.57 g/mol
Synonyms	14,20,22-Trihydroxy-1-oxoergosta-2,5,24-triene-18,26-dioic acid 18,20:26,22-dilactone; (22R)-Ergosta Dilactone Derivative; 1-Oxoergosta-2,5,24-triene dilactone; Steroidal Tricyclic Dilactone; 57423-72-0; UNII-9K5N8Q1F1M; 9K5N8Q1F1M
EINECS	Contact for details

Quality Control

Every batch of our (22R)-14,20,22-Trihydroxy-1-Oxoergosta-2,5,24-Triene-18,26-Dioic Acid 18,20:26,22-Dilactone is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay purity and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.