Description

Physalin F is a naturally occurring withanolide, a class of steroidal lactones, identified by the CAS number 57423-71-9. This compound is of significant interest for its potent biological activities, making it a valuable reference standard and research chemical for pharmaceutical and life science applications. It is primarily sought by researchers and developers in the fields of oncology, immunology, and natural product chemistry for its promising pharmacological profile.

Application

• Pharmaceutical Research & Development: Serves as a high-purity reference standard and active pharmaceutical ingredient (API) intermediate for investigating novel therapeutics.
• Oncology Studies: Used in preclinical research to study its cytotoxic and anti-proliferative effects against various cancer cell lines.
• Immunomodulation Research: Employed as a key compound in studies exploring its effects on inflammatory pathways and immune response modulation.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the quality control and standardization of plant extracts from the *Physalis* genus.
• Biochemical Assays: Utilized in enzyme inhibition studies and other target-based assays to elucidate its mechanism of action.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in chemistry, pharmacology, and botany.

Basic Information

Product Name	Physalin F
CAS No.	57423-71-9
Molecular Formula	C₂₈H₃₀O₁₀
Molecular Weight	526.53 g/mol
Synonyms	Physalin F; (1R,2S,10S,11S,13S,14R,15S,17S,18S,20R)-14,18-Dihydroxy-1,8,15-trimethyl-12-oxapentacyclo[9.7.1.0²,⁹.0¹¹,¹⁵.0¹³,¹⁷]nonadeca-4,6,8-trien-5,16-dione; Withaphysalin F; 5,6:18,20-Diepoxy-1,14-dihydroxy-4,4,8,13-tetramethyl-10-oxo-11-aza-3-oxapentacyclo[10.7.1.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]icosa-6,15-diene-16,17-dicarboxylic acid 16,17-lactone
EINECS	Contact for details

Quality Control

Our Physalin F is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider keeping the product under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.