Description

2'-Deoxyaristeromycin is a synthetic nucleoside analog derived from the natural product aristeromycin. This compound is a valuable biochemical tool and a key intermediate in antiviral and anticancer research, particularly in the study of S-adenosylhomocysteine (SAH) hydrolase inhibition. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents.

Application

• Biochemical Research: As a potent inhibitor of S-adenosylhomocysteine (SAH) hydrolase for studying methylation processes and epigenetic regulation.
• Antiviral Drug Discovery: Serves as a critical intermediate and reference standard in the development of broad-spectrum antiviral agents.
• Anticancer Research: Investigated for its potential to disrupt cellular metabolism and proliferation in various cancer cell lines.
• Enzymology Studies: Used as a substrate analog to study the mechanism and kinetics of nucleoside-processing enzymes.
• Pharmaceutical Intermediate: A key building block in the synthetic pathway for more complex nucleoside-based pharmaceuticals.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in HPLC and LC-MS.

Basic Information

Product Name	2'-Deoxyaristeromycin
CAS No.	57345-51-4
Molecular Formula	C11H15N5O3
Molecular Weight	265.27 g/mol
Synonyms	(1'R,2'S,3'R)-9-[2',3'-Dihydroxy-1'-(hydroxymethyl)cyclopent-4'-en-1'-yl]adenine; 2'-Deoxy-aristeromycin; 2'-Deoxyneplanocin A; 9-[(1'R,2'S,3'R)-2',3'-Dihydroxy-4'-cyclopenten-1'-yl]adenine; Adenine cyclopentenyl nucleoside analog; SAH Hydrolase Inhibitor II
EINECS	Contact for details

Quality Control

Our 2'-Deoxyaristeromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.