Description

Arachidonoyl Chloride is a high-purity, reactive fatty acid chloride derivative of arachidonic acid. This compound is a critical building block in organic synthesis and biochemical research, enabling the efficient introduction of the arachidonoyl moiety into target molecules. It is essential for researchers and manufacturers in the pharmaceutical, lipidomics, and specialty chemical industries developing bioactive compounds, lipid conjugates, and novel probes.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of arachidonoyl-containing drug candidates, prodrugs, and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used to prepare arachidonoylated proteins, peptides, and signaling lipids for studying lipid metabolism and cell signaling pathways.
• Probe & Conjugate Synthesis: Essential for creating fluorescent, biotinylated, or other tagged arachidonic acid derivatives for detection and assay development.
• Lipidomics Standard Preparation: Serves as a precursor for synthesizing internal standards and reference compounds used in mass spectrometry-based lipid analysis.
• Specialty Polymer & Material Science: Acts as a monomer or modifying agent for creating functional polymers with specific hydrophobic or bioactive properties.

Basic Information

Product Name	Arachidonoyl Chloride
CAS No.	57303-04-5
Molecular Formula	C20H31ClO
Molecular Weight	322.91 g/mol
Synonyms	5Z,8Z,11Z,14Z-Eicosatetraenoyl Chloride; Arachidonyl Chloride; Arachidonic Acid Chloride; 5,8,11,14-Eicosatetraenoyl Chloride; (all-Z)-5,8,11,14-Eicosatetraenoyl Chloride; 20:4(n-6) Fatty Acid Chloride; Eicosa-5,8,11,14-tetraenoyl Chloride
EINECS	Contact for details

Quality Control

Our Arachidonoyl Chloride is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for demanding research and synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its highly volatile and moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress and degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0% (Total Arachidonoyl species)
Acid Value	≤ 5.0 mg KOH/g
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.