Description

N4-Aminocytidine is a modified nucleoside building block of significant interest in advanced pharmaceutical and biochemical research. Its primary value lies in its role as a key intermediate for the synthesis of novel oligonucleotides and potential therapeutic agents, enabling precise molecular modifications. This high-purity compound is essential for researchers and manufacturers in the fields of nucleic acid chemistry, antiviral drug development, and molecular biology, where reliable quality and structural specificity are paramount.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Oligonucleotide Synthesis: Used in the research and development of modified RNA/DNA strands for therapeutic and diagnostic applications.
• Biochemical Research: Serves as a tool compound for studying enzyme mechanisms, such as those involving cytidine deaminases or other nucleoside-modifying enzymes.
• Proteomics & Genomics: Employed in the development of probes and labels for nucleic acid detection and sequencing technologies.
• Academic & Industrial R&D: Fundamental reagent for exploring new chemical biology pathways and drug discovery programs targeting nucleic acids.

Basic Information

Item	Details
Product Name	N4-Aminocytidine
CAS No.	57294-74-3
Molecular Formula	C9H14N4O5
Molecular Weight	258.23 g/mol
Synonyms	4-Aminocytidine; Cytidine, 4-amino-; 1-β-D-Ribofuranosyl-4-aminopyrimidin-2(1H)-one; 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone; N4-Aminocytidine; 4-Amino-1-(β-D-ribofuranosyl)cytosine; 4-Amino-1-(β-D-ribofuranosyl)-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our N4-Aminocytidine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.