Description

Cyclopropylmethyl Carbonochloridate is a specialized organic reagent belonging to the class of chloroformate esters. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the cyclopropylmethyloxycarbonyl (Cpmoc) protecting group. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the protection of amines and alcohols in multi-step synthesis of active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a coupling agent or for introducing the Cpmoc protecting group in solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Building block for creating novel herbicides, fungicides, and insecticides with cyclopropyl-containing structures.
• Material Science: Monomer or modifying agent in the synthesis of specialized polymers and functional materials.
• Chemical Biology: Tool compound for labeling and probing biological systems due to its reactive chloroformate moiety.
• Custom Synthesis & Contract Manufacturing: Essential reagent for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	Cyclopropylmethyl Carbonochloridate
CAS No.	57282-34-5
Molecular Formula	C5H7ClO2
Molecular Weight	134.56 g/mol
Synonyms	Cyclopropylmethyl chloroformate; Chloroformic acid cyclopropylmethyl ester; CPM-Chloroformate; Cyclopropanemethyl chloroformate; (Cyclopropylmethoxy)carbonyl chloride; Cpmoc-Cl; Cyclopropylmethyl chlorocarbonate; Carbonochloridic acid, cyclopropylmethyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropylmethyl Carbonochloridate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and research customers globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.