Description

Cyclohexanecarbonyl Chloride, 2-Isocyanato-, cis- (9Ci) is a specialized bifunctional reagent containing both an acid chloride and an isocyanate group on a cis-cyclohexane ring. This unique structure makes it a valuable building block for synthesizing complex molecules with defined stereochemistry and tailored properties. It is primarily sought by research and development chemists in the pharmaceutical and advanced materials sectors for creating novel polymers, active pharmaceutical ingredients (APIs), and high-performance coatings.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring a rigid, cis-cyclohexane scaffold for biological activity.
• Polymer & Resin Synthesis: Serves as a monomer or cross-linking agent for producing polyurethanes, polyamides, and other specialty polymers with enhanced thermal or mechanical properties.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging its reactive sites to create complex molecular architectures.
• Advanced Material Development: Employed in R&D for creating liquid crystals, specialty coatings, and adhesives where precise molecular geometry is critical.
• Chemical Synthesis Reagent: Acts as a versatile reagent in organic synthesis for introducing both carbonyl chloride and isocyanate functionalities in a single step.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 2-Isocyanato-, cis- (9Ci)
CAS No.	57266-58-7
Molecular Formula	C8H10ClNO2
Molecular Weight	187.62 g/mol
Synonyms	cis-2-Isocyanatocyclohexanecarbonyl Chloride; 2-Isocyanato-1-cyclohexanecarbonyl Chloride, cis-; cis-2-Isocyanatocyclohexanoyl Chloride; (1R,2S)-rel-2-Isocyanatocyclohexanecarbonyl Chloride; Cyclohexanecarbonyl chloride, 2-isocyanato-, (1R,2S)-rel-; 57266-58-7; cis-2-Isocyanato-cyclohexanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarbonyl Chloride, 2-Isocyanato-, cis- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and industrial applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize stability. Due to its moisture-sensitive (hygroscopic) nature and reactivity as a strong acid/organic solvent, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.