Description

2,5-Dichlorothiophene-3-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its dual functionality as a versatile building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is critically needed by research and development chemists, as well as process development teams, in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel thiophene-based drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used to build active molecules for crop protection products, such as herbicides and fungicides, leveraging the thiophene ring's bioactivity.
• Material Science: Serves as a monomer or functionalization agent in the production of conductive polymers, organic semiconductors, and advanced polymeric materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized heterocyclic dyes and pigments for high-performance applications.
• Chemical Research: A valuable reagent for academic and industrial R&D focused on developing new synthetic methodologies and exploring structure-activity relationships.
• Ligand and Catalyst Development: Used to create complex ligands for metal catalysis and organocatalysts.

Basic Information

Item	Details
Product Name	2,5-Dichlorothiophene-3-Carbonyl Chloride
CAS No.	57248-14-3
Molecular Formula	C5HCl3OS
Molecular Weight	211.48 g/mol
Synonyms	3-Chlorocarbonyl-2,5-dichlorothiophene; 2,5-Dichloro-3-thiophenecarbonyl chloride; 2,5-Dichlorothiophene-3-carboxylic acid chloride; 2,5-Dichloro-3-thienoyl chloride; 3-Carboxy-2,5-dichlorothiophene chloride; 2,5-Dichloro-3-thiophenecarbonylchloride; 2,5-Dichlorothiophene-3-carbonylchloride
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dichlorothiophene-3-Carbonyl Chloride is produced and tested under a strict quality management system. We ensure compliance with rigorous internal specifications, which are designed to meet the demanding requirements of fine chemical and pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.