Description

2,4,6-Triisopropylbenzoyl Chloride is a specialized acyl chloride derivative characterized by its sterically hindered aromatic structure. This compound is a critical reagent in organic synthesis, valued for its role as a highly effective acylating agent and a key building block for advanced intermediates. It is primarily sought by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered benzoate or benzamide moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its bulky structure imparts specific biological activity and stability.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Preparation: Employed in the synthesis of sophisticated ligands for transition metal catalysis and organocatalysts.
• Material Science Research: A precursor for developing novel organic electronic materials, liquid crystals, and advanced coatings.
• Custom Chemical Synthesis: An essential reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	2,4,6-Triisopropylbenzoyl Chloride
CAS No.	57199-00-5
Molecular Formula	C16H23ClO
Molecular Weight	266.80 g/mol
Synonyms	2,4,6-Triisopropylbenzoyl chloride; Mesitoyl chloride, 2,4,6-triisopropyl-; 2,4,6-Triisopropylbenzoic acid chloride; TIPB-Cl; 57199-00-5; Benzoic acid, 2,4,6-triisopropyl-, chloride
EINECS	Contact for details

Quality Control

Our production of 2,4,6-Triisopropylbenzoyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for extended shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.