Description

2'-o-Methyl-3-Deazauridine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and research tool for investigating RNA biology and developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, oncology research, and the study of nucleotide metabolism. The high-purity material is essential for ensuring reliable and reproducible experimental results in these demanding applications.

Application

• Antiviral Research: Investigated as a potential precursor or analog in the development of nucleoside-based antiviral therapies targeting RNA viruses.
• Oncology Research: Used in biochemical studies to understand cell proliferation and as a potential modulator in cancer-related pathways.
• Nucleotide Biochemistry: Serves as a valuable tool compound for studying enzyme mechanisms, such as those of nucleoside kinases and polymerases.
• RNA Synthesis & Modification: Employed in the synthesis of modified oligonucleotides to study RNA structure, function, and stability.
• Medicinal Chemistry: Acts as a key synthetic intermediate for the preparation of more complex nucleoside derivatives with enhanced biological activity.
• Academic & Industrial R&D: Fundamental research reagent in universities and biotech companies for probing nucleic acid chemistry and drug discovery.

Basic Information

Product Name	2'-o-Methyl-3-Deazauridine
CAS No.	57165-33-0
Molecular Formula	C10H13N3O5
Molecular Weight	255.23 g/mol
Synonyms	2'-O-Methyl-3-deazauridine; 1-(2-O-Methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; 3-Deaza-2'-O-methyluridine; 2'-OMe-3-deazauridine; 2'-O-Methyl-3-deazauridine; 1-(2-O-Methyl-β-D-ribofuranosyl)-1,2-dihydropyrimidine-2,4(3H)-dione; 3-Deaza-2'-O-methyl-uridine
EINECS	Contact for details

Quality Control

Our 2'-o-Methyl-3-Deazauridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.