Description

2-Amino-5-β-D-Ribofuranosyl-4(1H)-Pyrimidinone Hydrochloride is a high-purity nucleoside derivative, essential as a critical building block in pharmaceutical research and development. Its primary value lies in its role as a key synthetic intermediate for novel antiviral and anticancer agents, particularly in the synthesis of modified nucleoside analogs. This compound is vital for research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis.
• Antiviral Drug Development: Serves as a key scaffold for the research and development of drugs targeting viral polymerases.
• Oncology Research: Investigated for the development of chemotherapeutic agents that interfere with cancer cell proliferation.
• Pro-drug Synthesis: Utilized in the design and synthesis of nucleoside-based pro-drugs to enhance bioavailability and targeting.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Amino-5-β-D-Ribofuranosyl-4(1H)-Pyrimidinone Hydrochloride
CAS No.	57100-20-6
Molecular Formula	C9H14N3O5 • HCl
Molecular Weight	279.68 g/mol (Free base: 244.22 g/mol)
Synonyms	2-Amino-5-β-D-ribofuranosyl-4(1H)-pyrimidinone hydrochloride; 2-Amino-4-hydroxy-5-(β-D-ribofuranosyl)pyrimidine hydrochloride; 5-(β-D-Ribofuranosyl)isocytosine hydrochloride; Isocytidine hydrochloride; Iso-dC hydrochloride; 5-Ribosylisocytosine hydrochloride; NSC 20112 hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-5-β-D-Ribofuranosyl-4(1H)-Pyrimidinone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.