Description

Pseudoisocytidine is a synthetic nucleoside analog of cytidine, where the nitrogen atoms in the pyrimidine ring are repositioned. This unique structural modification makes it a valuable building block and research chemical in advanced pharmaceutical and biochemical applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in oligonucleotide synthesis, antisense therapy development, and nucleic acid research. The compound, identified as CAS NO 57100-18-2, is essential for probing nucleic acid structure and function and for developing novel therapeutic agents.

Application

• Oligonucleotide Synthesis: Serves as a modified nucleoside precursor for introducing specific structural motifs into synthetic DNA and RNA strands.
• Antisense & RNAi Research: Used in the development of antisense oligonucleotides and siRNA molecules to enhance stability and binding affinity.
• Medicinal Chemistry: Acts as a key intermediate in the research and development of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Employed as a tool compound to study enzyme mechanisms, nucleic acid-protein interactions, and genetic code expansion.
• Diagnostic Probe Development: Utilized in the design of fluorescently labeled or otherwise tagged probes for genetic testing and molecular diagnostics.

Basic Information

Product Name	Pseudoisocytidine
CAS No.	57100-18-2
Molecular Formula	C9H13N3O5
Molecular Weight	243.22 g/mol
Synonyms	4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,2-dihydropyrimidin-2-one; 5-Aza-2'-deoxycytidine analog; psi-Cytidine; 1-(β-D-Ribofuranosyl)-2-oxo-4-amino-5-azapyrimidine; 4-Amino-1-β-D-ribofuranosyl-1,2-dihydro-2-oxo-5-azapyrimidine; Pseudoisocytidine, 5-Aza-isocytidine
EINECS	Contact for details

Quality Control

Our Pseudoisocytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements. Specifications are designed to meet the high standards of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.