Description

(α-Formyloxy)Phenyl Acetyl Chloride is a specialized acyl chloride derivative used as a key building block in advanced organic synthesis. Its primary value lies in its dual functional groups, enabling efficient acylation and formylation reactions in a single molecule. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecular scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a phenyl acetyl moiety with a protected formyl group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where its reactive chloride facilitates the formation of amide or ester bonds.
• Peptide Chemistry: Serves as an acylating agent for the introduction of modified amino acid side chains or protecting groups in peptide synthesis.
• Material Science: Employed in the surface modification of polymers and the creation of specialty monomers for high-performance resins.
• Chemical Research: A versatile building block in academic and industrial R&D for exploring new reaction pathways and creating novel heterocyclic compounds.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic colorants and photoactive materials.

Basic Information

Product Name	(α-Formyloxy)Phenyl Acetyl Chloride
CAS No.	57079-45-5
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	2-(Formyloxy)-2-phenylacetyl chloride; α-(Formyloxy)benzeneacetyl chloride; Phenylglyoxylic acid formate chloride; (Formyloxy)(phenyl)acetyl chloride; NSC 403119; 2-Phenyl-2-(formyloxy)acetyl chloride; α-Formyloxy-α-phenylacetyl chloride
EINECS	Contact for details

Quality Control

Our (α-Formyloxy)Phenyl Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.