Description

4,5-Thiazoledicarbonyl Dichloride (9Ci) is a versatile and highly reactive organic intermediate, primarily valued for its role as a key building block in heterocyclic synthesis. Its significance lies in its ability to introduce the thiazole moiety, a privileged scaffold in medicinal chemistry, into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of thiazole-containing drug candidates, including potential antivirals, antibiotics, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiazole ring contributes to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for metal catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and fine chemical companies performing custom synthesis projects.

Basic Information

Product Name	4,5-Thiazoledicarbonyl Dichloride (9Ci)
CAS No.	57062-18-7
Molecular Formula	C5HCl2NO2S
Molecular Weight	198.03 g/mol
Synonyms	4,5-Thiazoledicarboxylic acid dichloride; Thiazole-4,5-dicarbonyl dichloride; 4,5-Dichlorocarbonylthiazole; 1,3-Thiazole-4,5-dicarbonyl dichloride; 4,5-Thiazoledicarboxylic acid chloride; 4,5-Thiazoledicarboxylic dichloride; 4,5-Thiazoledicarbonyl chloride
EINECS	Contact for details

Quality Control

Our 4,5-Thiazoledicarbonyl Dichloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.