Description

4-Azidophenacyl Bromide is a specialized organic compound featuring both an azide and a phenacyl bromide functional group, making it a versatile photoaffinity labeling and crosslinking reagent. This dual functionality is critical for researchers developing probes to study biomolecular interactions and for synthesizing advanced materials. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, bioconjugation, and polymer chemistry sectors for photo-induced covalent bonding applications.

Application

• Photoaffinity Labeling: A key reagent for covalently tagging biological targets (e.g., proteins, enzymes) upon UV irradiation to study binding sites and mechanisms.
• Bioconjugation & Probe Synthesis: Used to create crosslinked biomolecules and fluorescent or affinity probes for diagnostic and research applications.
• Polymer & Material Science: Serves as a photoinitiator or crosslinker in the synthesis of specialty polymers, hydrogels, and surface-modified materials.
• Chemical Biology Research: Enables the study of protein-protein and protein-ligand interactions through irreversible photo-crosslinking.
• Pharmaceutical Intermediate: Acts as a building block in the synthesis of more complex molecules for drug discovery programs.
• Surface Immobilization: Facilitates the covalent attachment of biomolecules to chips, beads, or other solid supports for assay development.

Basic Information

Product Name	4-Azidophenacyl Bromide
CAS No.	57018-46-9
Molecular Formula	C8H6BrN3O
Molecular Weight	240.06 g/mol
Synonyms	p-Azidophenacyl Bromide; 2-Bromo-1-(4-azidophenyl)ethanone; 4-Azidophenacylbromide; 1-(4-Azidophenyl)-2-bromoethanone; α-Bromo-4-azidoacetophenone; Phenacyl bromide, 4-azido-; Azidophenacyl Bromide; Photoaffinity Labeling Reagent ABr
EINECS	Contact for details

Quality Control

Our 4-Azidophenacyl Bromide is produced under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the exacting standards of pharmaceutical and biotech research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at temperatures between 2°C and 8°C (refrigerated) for long-term stability. This compound is light-sensitive (store away from light). Allow the container to reach room temperature before opening to minimize condensation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.