Description

8-Methyladenosine is a chemically modified nucleoside derivative of adenosine, featuring a methyl group at the 8-position of the purine ring. This specific modification makes it a valuable intermediate and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying RNA modification, enzyme mechanisms, and as a building block for novel therapeutic agents.

Application

• Biochemical Research: Critical intermediate in the study of RNA methylation, epigenetics, and nucleoside metabolism.
• Pharmaceutical Reference Standard: Used as a high-purity standard for quality control and analytical method development in drug discovery.
• Enzymology Studies: Serves as a substrate or inhibitor for investigating the activity of methyltransferases and other nucleic acid-modifying enzymes.
• Nucleoside Analog Synthesis: A key precursor in the chemical synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Diagnostic Reagent Development: Employed in the formulation of reagents for molecular diagnostics and research kits.

Basic Information

Product Name	8-Methyladenosine
CAS No.	56973-12-7
Molecular Formula	C11H15N5O4
Molecular Weight	281.27 g/mol
Synonyms	8-Methyladenosine; N6-Methyladenosine (common misassignment, clarify position); 9-β-D-Ribofuranosyl-8-methyladenine; Adenosine, 8-methyl-; 8-Methyl-9-β-D-ribofuranosyladenine; 8-MeA; 8-MA
EINECS	Contact for details

Quality Control

Our 8-Methyladenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.