Description

5'-Deoxy-5-Methyluridine is a modified nucleoside derivative, a key building block in nucleic acid chemistry and pharmaceutical research. Its structural modification makes it a valuable intermediate for the synthesis of novel antiviral and anticancer agents, as well as for biochemical studies. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing nucleoside-based therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and repair.
• Pro-drug Development: Serves as a precursor in the design of nucleoside pro-drugs to enhance bioavailability and targeting.
• Antisense Oligonucleotide Synthesis: Incorporated into oligonucleotide sequences to modify their stability, binding affinity, or biological activity.
• Reference Standard: Employed as an analytical standard in quality control and method development for pharmaceutical manufacturing.
• Life Science Tools: Used in the development of molecular probes and labeled compounds for diagnostic and research applications.

Basic Information

Product Name	5'-Deoxy-5-Methyluridine
CAS No.	56971-08-5
Molecular Formula	C10H14N2O5
Molecular Weight	242.23 g/mol
Synonyms	5-Methyl-2'-deoxyuridine; 5-Methyldeoxyuridine; Thymidine, 2'-deoxy-; 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil; 5-Methyl-1-(2-deoxy-β-D-ribofuranosyl)uracil; dT (ambiguous, can refer to thymidine); 5-Methyldeoxyuridine (common name); 2'-Deoxy-5-methyluridine
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5-Methyluridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.